SOME HYDANTOIN DERIVATIVES

The Behavior of Some Hydantoin Derivatives in Metabolism

Despite frequent investigations the problem of the mechanism of uricolysis still remains unsolved. The attempts to identify those substances, whose formation by oxidative agents from uric acid or the purines is easily accomplished by the organic chemist, as products of the. intermediary metabolism of uric acid have failed; nor has the study of these same substances in metabolism thrown addition...

Facile Synthesis of Hydantoin Derivatives under Microwave Irradiation

In recent years, microwave irradiation using commercial domestic ovens for the optimization and acceleration of organic reactions has rapidly increased1−2.It has been reported that a variety of reactions such as Dielsalder , ene, Claisen reactions , Fischer cyclization, synthesis of heterocycles , hydrolysis of esters , hydrogenation, deprotection of benzyl ester, deacetylation of diacetates, o...

Some derivatives of dibenzothiophene.

Effects of sulfur-containing hydantoin derivatives on metabolism of Ehrlich ascites carcinoma.

A number of structurally related hydantoins has been examined for their effects on the metabolic activities of Ehrlieh aseites carcinoma cells. 5-Ethylsulfinylmethylhydantoin [ESH] was a potent inhibitor of such activities. 5-Ethylsulfonylmethylhydantoin had less activity, and the other hydantoins tested were without effect. ESH was also a potent inhibitor of metabolism in Salk "altered" monkey...

Effects of Sulfur-containing Hydantoin Derivatives on Metabolism of Ehrlich Ascites Carcinoma

A number of structurally related hydantoins has been examined for their effects on the metabolic activities of Ehrlieh aseites carcinoma cells. 5-Ethylsulfinylmethylhydantoin [ESH] was a potent inhibitor of such activities. 5-Ethylsulfonylmethylhydantoin had less activity, and the other hydantoins tested were without effect. ESH was also a potent inhibitor of metabolism in Salk "altered" monkey...